D
IPR000937

Icosahedral viral capsid protein, S domain

InterPro entry
Short nameCapsid_prot_S-dom_vir
Overlapping
homologous
superfamilies
 

Description

The capsid proteins of plant icosahedral positive strand RNA viruses form 4 different domains, a positively charged, N-terminal 'R' domain, which interacts with RNA (66 residues); a connecting arm, 'a' (35 residues); a central, surface 'S' domain, which forms the virion shell; and a projecting, C-terminal 'P' domain
[1]
. Some of the viruses lack either the R or P domains. The S domain contains from 158 to 166 amino acids and comprises 8 anti-parallel β-strands, which form a twisted sheet or jelly-roll fold. This structure is shared by a number of plant viral capsid proteins, which include: Carmovirus, Dianthovirus, Sobemovirus, Tombusvirus and an unidentified tobacco necrosis virus
[2]
.

References

1.The three-dimensional distribution of RNA and protein in the interior of tomato bushy stunt virus: a neutron low-resolution single-crystal diffraction study. Timmins PA, Wild D, Witz J. Structure 2, 1191-201, (1994). View articlePMID: 7704529

2.Phylogeny of capsid proteins of small icosahedral RNA plant viruses. Dolja VV, Koonin EV. J. Gen. Virol. 72 ( Pt 7), 1481-6, (1991). PMID: 1856686

GO terms

biological process

  • None

cellular component

Cross References

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