AGC-kinase, C-terminal
Short name | AGC-kinase_C |
Overlapping homologous superfamilies | |
domain relationships |
Description
* Serine/threonine-protein kinases
* Tyrosine-protein kinases
* Dual specificity protein kinases (e.g. MEK -phosphorylates both Thr and Tyr on target proteins)
References
1.The protein kinase complement of the human genome. Manning G, Whyte DB, Martinez R, Hunter T, Sudarsanam S. Science 298, 1912-34, (2002). View articlePMID: 12471243
2.Regulation of the ABC kinases by phosphorylation: protein kinase C as a paradigm. Newton AC. Biochem. J. 370, 361-71, (2003). View articlePMID: 12495431
3.AGC protein kinase phosphorylation and protein kinase C. Parker PJ, Parkinson SJ. Biochem. Soc. Trans. 29, 860-3, (2001). View articlePMID: 11709088
4.PDK1, the master regulator of AGC kinase signal transduction. Mora A, Komander D, van Aalten DM, Alessi DR. Semin. Cell Dev. Biol. 15, 161-70, (2004). View articlePMID: 15209375
5.Crystal structure of an activated Akt/protein kinase B ternary complex with GSK3-peptide and AMP-PNP. Yang J, Cron P, Good VM, Thompson V, Hemmings BA, Barford D. Nat. Struct. Biol. 9, 940-4, (2002). View articlePMID: 12434148
6.The protein kinase family: conserved features and deduced phylogeny of the catalytic domains. Hanks SK, Quinn AM, Hunter T. Science 241, 42-52, (1988). View articlePMID: 3291115
7.Evolution of protein kinase signaling from yeast to man. Manning G, Plowman GD, Hunter T, Sudarsanam S. Trends Biochem. Sci. 27, 514-20, (2002). View articlePMID: 12368087
8.High-throughput structural biology in drug discovery: protein kinases. Stout TJ, Foster PG, Matthews DJ. Curr. Pharm. Des. 10, 1069-82, (2004). View articlePMID: 15078142
9.Creating chemical diversity to target protein kinases. Li B, Liu Y, Uno T, Gray N. Comb. Chem. High Throughput Screen. 7, 453-72, (2004). View articlePMID: 15320712
GO terms
biological process
cellular component
- None