Peptidase M2, peptidyl-dipeptidase A
Short name | Peptidase_M2 |
Description
References
1.The emerging role of ACE2 in physiology and disease. Hamming I, Cooper ME, Haagmans BL, Hooper NM, Korstanje R, Osterhaus AD, Timens W, Turner AJ, Navis G, van Goor H. J. Pathol. 212, 1-11, (2007). View articlePMID: 17464936
2.ACE2 X-ray structures reveal a large hinge-bending motion important for inhibitor binding and catalysis. Towler P, Staker B, Prasad SG, Menon S, Tang J, Parsons T, Ryan D, Fisher M, Williams D, Dales NA, Patane MA, Pantoliano MW. J. Biol. Chem. 279, 17996-8007, (2004). View articlePMID: 14754895
3.The two homologous domains of human angiotensin I-converting enzyme are both catalytically active. Wei L, Alhenc-Gelas F, Corvol P, Clauser E. J. Biol. Chem. 266, 9002-8, (1991). View articlePMID: 1851160
4.Evolutionary families of metallopeptidases. Rawlings ND, Barrett AJ. Meth. Enzymol. 248, 183-228, (1995). View articlePMID: 7674922
5.The structure of testis angiotensin-converting enzyme in complex with the C domain-specific inhibitor RXPA380. Corradi HR, Chitapi I, Sewell BT, Georgiadis D, Dive V, Sturrock ED, Acharya KR. Biochemistry 46, 5473-8, (2007). View articlePMID: 17439247
6.Probing the basis of domain-dependent inhibition using novel ketone inhibitors of Angiotensin-converting enzyme. Watermeyer JM, Kroger WL, O'Neill HG, Sewell BT, Sturrock ED. Biochemistry 47, 5942-50, (2008). View articlePMID: 18457420
Further reading
7. Crystal structure of Drosophila angiotensin I-converting enzyme bound to captopril and lisinopril. Kim HM, Shin DR, Yoo OJ, Lee H, Lee JO. FEBS Lett. 538, 65-70, (2003). View articlePMID: 12633854
8. Toward a role for angiotensin-converting enzyme in insects. Isaac RE, Schoofs L, Williams TA, Corvol P, Veelaert D, Sajid M, Coates D. Ann. N. Y. Acad. Sci. 839, 288-92, (1998). View articlePMID: 9629165
9. Crystal structure of the human angiotensin-converting enzyme-lisinopril complex. Natesh R, Schwager SL, Sturrock ED, Acharya KR. Nature 421, 551-4, (2003). View articlePMID: 12540854
10. Crystal structure of the N domain of human somatic angiotensin I-converting enzyme provides a structural basis for domain-specific inhibitor design. Corradi HR, Schwager SL, Nchinda AT, Sturrock ED, Acharya KR. J. Mol. Biol. 357, 964-74, (2006). View articlePMID: 16476442
11. Characterization of the first non-insect invertebrate functional angiotensin-converting enzyme (ACE): leech TtACE resembles the N-domain of mammalian ACE. Riviere G, Michaud A, Deloffre L, Vandenbulcke F, Levoye A, Breton C, Corvol P, Salzet M, Vieau D. Biochem J 382, 565-73, (2004). PMID: 15175004
12. The angiotensin-converting enzyme (ACE) gene family of Anopheles gambiae. Burnham S, Smith JA, Lee AJ, Isaac RE, Shirras AD. BMC Genomics 6, 172, (2005). View articlePMID: 16329762
13. [Structure and function of angiotensin converting enzyme and its inhibitors]. Zhao Y, Xu C. Sheng Wu Gong Cheng Xue Bao 24, 171-6, (2008). View articlePMID: 18464595
14. An essential role in molting and morphogenesis of Caenorhabditis elegans for ACN-1, a novel member of the angiotensin-converting enzyme family that lacks a metallopeptidase active site. Brooks DR, Appleford PJ, Murray L, Isaac RE. J Biol Chem 278, 52340-6, (2003). View articlePMID: 14559923
15. ACE2 and ACE: structure-based insights into mechanism, regulation and receptor recognition by SARS-CoV. Lubbe L, Cozier GE, Oosthuizen D, Acharya KR, Sturrock ED. Clin Sci (Lond) 134, 2851-2871, (2020). View articlePMID: 33146371
16. Residues affecting the chloride regulation and substrate selectivity of the angiotensin-converting enzymes (ACE and ACE2) identified by site-directed mutagenesis. Rushworth CA, Guy JL, Turner AJ. FEBS J 275, 6033-42, (2008). View articlePMID: 19021774
17. Structural diversity of angiotensin-converting enzyme. Bingham RJ, Dive V, Phillips SE, Shirras AD, Isaac RE. FEBS J 273, 362-73, (2006). View articlePMID: 16403023
18. A new high-resolution crystal structure of the Drosophila melanogaster angiotensin converting enzyme homologue, AnCE. Harrison C, Acharya KR. FEBS Open Bio 5, 661-7, (2015). View articlePMID: 26380810
GO terms
biological process
cellular component
Cross References
ENZYME
Genome Properties