D
IPR001761

Periplasmic binding protein/LacI sugar binding domain

InterPro entry
Short namePeripla_BP/Lac1_sug-bd_dom
Overlapping
homologous
superfamilies
 

Description

This entry represents periplasmic binding proteins, and the LacI family of transcriptional regulators sugar binding domain. The periplasmic binding proteins are the primary receptors for chemotaxis and transport of many sugar based solutes. The LacI family of proteins consist of transcriptional regulators related to the lac repressor. In this case, generally the sugar binding domain binds a sugar which changes the DNA binding activity of the repressor domain (lacI)
[1, 2]
.

References

1.1.7 A X-ray structure of the periplasmic ribose receptor from Escherichia coli. Mowbray SL, Cole LB. J. Mol. Biol. 225, 155-75, (1992). View articlePMID: 1583688

2.Crystal structure of the lactose operon repressor and its complexes with DNA and inducer. Lewis M, Chang G, Horton NC, Kercher MA, Pace HC, Schumacher MA, Brennan RG, Lu P. Science 271, 1247-54, (1996). View articlePMID: 8638105

Cross References

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