Dihydrofolate reductase domain
Short name | DHFR_dom |
Overlapping homologous superfamilies |
Description
References
1.A gene for dihydrofolate reductase in a herpesvirus. Trimble JJ, Murthy SC, Bakker A, Grassmann R, Desrosiers RC. Science 239, 1145-7, (1988). View articlePMID: 2830673
2.Crystal structure of human dihydrofolate reductase complexed with folate. Oefner C, D'Arcy A, Winkler FK. Eur. J. Biochem. 174, 377-85, (1988). View articlePMID: 3383852
3.Porcine liver dihydrofolate reductase. Purification, properties, and amino acid sequence. Smith SL, Patrick P, Stone D, Phillips AW, Burchall JJ. J. Biol. Chem. 254, 11475-84, (1979). View articlePMID: 500653
4.Crystal structures of Escherichia coli and Lactobacillus casei dihydrofolate reductase refined at 1.7 A resolution. I. General features and binding of methotrexate. Bolin JT, Filman DJ, Matthews DA, Hamlin RC, Kraut J. J. Biol. Chem. 257, 13650-62, (1982). View articlePMID: 6815178
5.Antifolate drug selection results in duplication and rearrangement of chromosome 7 in Plasmodium chabaudi. Cowman AF, Lew AM. Mol. Cell. Biol. 9, 5182-8, (1989). View articlePMID: 2601715
GO terms
biological process
molecular function
cellular component
- None
Cross References
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Genome Properties