IPR001819
Chromogranin A/B
InterPro entry
Short name | Chromogranin_AB |
family relationships |
Description
Chromogranins and secretogranins are acidic proteins present in the secretory granules of endocrine and neuro-endocrine cells
[1, 2]. Granins may be precursors of biologically-active peptides, or they may be helper proteins in the packaging of peptide hormones and neuropeptides - their precise role is unclear.
Chromogranins A and B are characterised by an N-terminal motif that includes 2 cysteine residues involved in disulphide bond formation.
References
1.The granin (chromogranin/secretogranin) family. Huttner WB, Gerdes HH, Rosa P. Trends Biochem. Sci. 16, 27-30, (1991). View articlePMID: 2053134
2.Biochemistry of the chromogranin A protein family. Simon JP, Aunis D. Biochem. J. 262, 1-13, (1989). View articlePMID: 2684154
GO terms
Cross References
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