F
IPR002119

Histone H2A

InterPro entry
Short nameHistone_H2A
Overlapping
homologous
superfamilies
 
Histone-fold (IPR009072)
family relationships

Description

Histone H2A is a small, highly conserved nuclear protein that, together with two molecules each of histones H2B, H3 and H4, forms the eukaryotic nucleosome core
[1]
; the nucleosome octamer winds ~146 DNA base-pairs. In the mouse, histone H2A can be replaced by histone H2A-like 1
[2]
.

References

1.Phylogenetic analysis of the core histones H2A, H2B, H3, and H4. Thatcher TH, Gorovsky MA. Nucleic Acids Res. 22, 174-9, (1994). View articlePMID: 8121801

2.Pericentric heterochromatin reprogramming by new histone variants during mouse spermiogenesis. Govin J, Escoffier E, Rousseaux S, Kuhn L, Ferro M, Thevenon J, Catena R, Davidson I, Garin J, Khochbin S, Caron C. J. Cell Biol. 176, 283-94, (2007). View articlePMID: 17261847

GO terms

Cross References

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