IPR002406
Natriuretic peptide, C type
InterPro entry
Short name | C_natriurtcpep |
family relationships |
Description
A disulphide bond resident in the C-terminal section is required for full activity of atriopeptins. The family of NPs includes structurally-related peptides that elicit similar pharmacological spectra. Amongst these are brain natriuretic peptide (BNP); C-type natriuretic peptide (CNP); ventricular natriuretic peptide (VNP)
[3]; and Dendroaspis angusticeps (Eastern green mamba) natriuretic peptide (DNP)
[4].
C-type natriuretic peptide has vasorelaxant and cGMP-stimulating activities.
References
1.Atrial natriuretic factor and related peptide hormones. Rosenzweig A, Seidman CE. Annu. Rev. Biochem. 60, 229-55, (1991). View articlePMID: 1652921
2.Atrial natriuretic factor. Inagami T. J. Biol. Chem. 264, 3043-6, (1989). View articlePMID: 2536732
3.A novel natriuretic peptide isolated from eel cardiac ventricles. Takei Y, Takahashi A, Watanabe TX, Nakajima K, Sakakibara S. FEBS Lett. 282, 317-20, (1991). View articlePMID: 1828035
4.A new member of the natriuretic peptide family is present in the venom of the green mamba (Dendroaspis angusticeps). Schweitz H, Vigne P, Moinier D, Frelin C, Lazdunski M. J. Biol. Chem. 267, 13928-32, (1992). View articlePMID: 1352773
GO terms
biological process
- None
molecular function
cellular component
Contributing Member Database Entry
- PRINTS:PR00713