F
IPR002594

Glycoside hydrolase family 12

InterPro entry
Short nameGH12
Overlapping
homologous
superfamilies
 

Description

Glycoside hydrolase family 12
GH12
comprises enzymes with two known activities: Endo-β-1,4-glucanase (
3.2.1.4
) and Xyloglucan-specific endo-β-1,4-glucanase / endo-xyloglucanase (
3.2.1.151
). These enzymes were formerly known as cellulase family H.

O-Glycosyl hydrolases (
3.2.1.
) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families
[2, 1]
. This classification is available on the CAZy (CArbohydrate-Active EnZymes) website.

References

1.Structures and mechanisms of glycosyl hydrolases. Davies G, Henrissat B. Structure 3, 853-9, (1995). View articlePMID: 8535779

2.Conserved catalytic machinery and the prediction of a common fold for several families of glycosyl hydrolases. Henrissat B, Callebaut I, Fabrega S, Lehn P, Mornon JP, Davies G. Proc. Natl. Acad. Sci. U.S.A. 92, 7090-4, (1995). View articlePMID: 7624375

GO terms

cellular component

  • None

Cross References

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