IPR002734
Bacterial bifunctional deaminase-reductase, C-terminal
InterPro entry
Short name | RibDG_C |
Overlapping homologous superfamilies | |
domain relationships |
Description
This domain is found in the C terminus of the bifunctional deaminase-reductase of Escherichia coli, Bacillus subtilis and other bacteria in combination with
IPR002125 that catalyses the second and third steps in the biosynthesis of riboflavin, i.e., the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (deaminase) and the subsequent reduction of the ribosyl side chain (reductase)
[1]. The domain is also present in some HTP reductases from archaea and fungi.
References
1.Biosynthesis of riboflavin: characterization of the bifunctional deaminase-reductase of Escherichia coli and Bacillus subtilis. Richter G, Fischer M, Krieger C, Eberhardt S, Luttgen H, Gerstenschlager I, Bacher A. J. Bacteriol. 179, 2022-8, (1997). View articlePMID: 9068650
GO terms
biological process
molecular function
cellular component
- None
Cross References
Contributing Member Database Entry
- Pfam:PF01872
Representative structure
5xv0: Crystal structure of Rib7 mutant D33N from Methanosarcina mazei