F
IPR003120

Transcription factor Ste12

InterPro entry
Short nameSte12

Description

This entry include a group of fungal transcription factors, including Ste12, Cph1, SteA and MST12. In S. cerevisiae, Ste12 mediates transcriptional induction of cell type-specific genes in response to pheromones
[2, 1]
. Aspergillus nidulans SteA, an homodomain-containing protein, is required for sexual reproduction
[3]
. MST12 from Magnaporthe oryzae (rice blast fungus) may regulate genes involved in infectious hyphae growth
[4]
and in the expression of the cell surface sensor MSB2
[5]
.

References

1.Coupling of cell identity to signal response in yeast: interaction between the alpha 1 and STE12 proteins. Yuan YO, Stroke IL, Fields S. Genes Dev. 7, 1584-97, (1993). View articlePMID: 8339934

2.STE12, a protein involved in cell-type-specific transcription and signal transduction in yeast, is part of protein-DNA complexes. Errede B, Ammerer G. Genes Dev. 3, 1349-61, (1989). View articlePMID: 2558054

3.Aspergillus SteA (sterile12-like) is a homeodomain-C2/H2-Zn+2 finger transcription factor required for sexual reproduction. Vallim MA, Miller KY, Miller BL. Mol. Microbiol. 36, 290-301, (2000). View articlePMID: 10792717

4.MST12 regulates infectious growth but not appressorium formation in the rice blast fungus Magnaporthe grisea. Park G, Xue C, Zheng L, Lam S, Xu JR. Mol Plant Microbe Interact 15, 183-92, (2002). PMID: 11952120

5.Multiple plant surface signals are sensed by different mechanisms in the rice blast fungus for appressorium formation. Liu W, Zhou X, Li G, Li L, Kong L, Wang C, Zhang H, Xu JR. PLoS Pathog 7, e1001261, (2011). PMID: 21283781

GO terms

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