IPR003382
Flavoprotein
InterPro entry
Short name | Flavoprotein |
Overlapping homologous superfamilies |
Description
This entry contains a diverse range of flavoprotein enzymes, including epidermin biosynthesis protein, EpiD, which has been shown to be a flavoprotein that binds FMN
[1]. This enzyme catalyzes the removal of two reducing equivalents from the cysteine residue of the C-terminal meso-lanthionine of epidermin to form a --C==C-- double bond. This family also includes the B chain of dipicolinate synthase a small polar molecule that accumulates to high concentrations in bacterial endospores, and is thought to play a role in spore heat resistance, or the maintenance of heat resistance
[2]. Dipicolinate synthase catalyses the formation of dipicolinic acid from dihydroxydipicolinic acid. This family also includes phenylacrylic acid decarboxylase
4.1.1.
References
1.Purification and characterization of EpiD, a flavoprotein involved in the biosynthesis of the lantibiotic epidermin. Kupke T, Stevanovic S, Sahl HG, Gotz F. J. Bacteriol. 174, 5354-61, (1992). View articlePMID: 1644762
2.Cloning, DNA sequence, functional analysis and transcriptional regulation of the genes encoding dipicolinic acid synthetase required for sporulation in Bacillus subtilis. Daniel RA, Errington J. J. Mol. Biol. 232, 468-83, (1993). View articlePMID: 8345520
3.PAD1 encodes phenylacrylic acid decarboxylase which confers resistance to cinnamic acid in Saccharomyces cerevisiae. Clausen M, Lamb CJ, Megnet R, Doerner PW. Gene 142, 107-12, (1994). View articlePMID: 8181743
GO terms
Cross References
Contributing Member Database Entry
- Pfam:PF02441