F
IPR003444

Transcriptional regulator MraZ

InterPro entry
Short nameMraZ
Overlapping
homologous
superfamilies
 
MraZ superfamily (IPR038619)

Description

This entry represents the MraZ protein from bacteria. This protein often is found with other genes of the dcw (division cell wall) gene cluster, including mraW, ftsI, murE, murF, ftsW, murG, etc. In E. coli, MraZ is a DNA-binding transcription factor
[1]
. It acts as a repressor of Pmra, which is a promoter for mraZ and mraW. It also regulates the expression of genes outside the dcw cluster. Overproduction of Escherichia coli MraZ inhibits cell division
[1]
.

References

1.The highly conserved MraZ protein is a transcriptional regulator in Escherichia coli. Eraso JM, Markillie LM, Mitchell HD, Taylor RC, Orr G, Margolin W. J. Bacteriol. 196, 2053-66, (2014). View articlePMID: 24659771

GO terms

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