F
IPR004277

Phosphatidyl serine synthase

InterPro entry
Short namePSS

Description

Phosphatidyl serine synthase is also known as serine exchange enzyme (
2.7.8
). This family represents eukaryotic PSS I and II, membrane bound proteins that catalyse the replacement of the head group of a phospholipid (phosphotidylcholine or phosphotidylethanolamine) by L-serine
[1]
.

Proteins in this entry include Pss from Drosophila melanogaster. Pss has been shown to regulate cell growth, lipid storage and mitochondrial function
[2]
.

References

1.Phosphatidylserine synthase I and II of mammalian cells. Kuge O, Nishijima M. Biochim. Biophys. Acta 1348, 151-6, (1997). View articlePMID: 9370327

2.Phosphatidylserine synthase regulates cellular homeostasis through distinct metabolic mechanisms. Yang X, Liang J, Ding L, Li X, Lam SM, Shui G, Ding M, Huang X. PLoS Genet. 15, e1008548, (2019). PMID: 31869331

GO terms

Cross References

Contributing Member Database Entry
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