IPR004402
Purine nucleoside phosphorylase DeoD-type
InterPro entry
Short name | DeoD-type |
Overlapping homologous superfamilies |
Description
Purine nucleoside phosphorylase
2.4.2.1, also called inosine phosphorylase (pnp), catalyses the cleavage of the glycosidic bond of ribo- and deoxyribonucleosides in the presence of orthophospate
[1]. It is specific for guanosine, inosine and adenosine and cleavage results in formation of their respective bases and ribose phosphate molecules. Together with adenosine deanimase,
IPR006330, purine nucleoside phophorylase is responsible for purine catabolism as part of the salvage pathway of nucleotides and nucleosides.
References
1.Purine nucleoside phosphorylases: properties, functions, and clinical aspects. Bzowska A, Kulikowska E, Shugar D. Pharmacol. Ther. 88, 349-425, (2000). View articlePMID: 11337031
GO terms
biological process
molecular function
cellular component
- None
Cross References
ENZYME
Genome Properties
Representative structure
7op9: Purine nucleoside phosphorylase(DeoD-type) from H. pylori with 2,6-dichloropurine