D
IPR004443

YjeF N-terminal domain

InterPro entry
Short nameYjeF_N_dom
Overlapping
homologous
superfamilies
 

Description

In bacteria or archaea, YjeF N-terminal domains occur either as single domain proteins or fused with other domains and are commonly associated with enzymes. YjeF N-terminal domains (also known as NAD(P)H-hydrate epimerase) are often fused to a YjeF C-terminal domain. It is a bifunctional enzyme that catalyses the epimerisation of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP
[1]
.

References

1.Extremely conserved ATP- or ADP-dependent enzymatic system for nicotinamide nucleotide repair. Marbaix AY, Noel G, Detroux AM, Vertommen D, Van Schaftingen E, Linster CL. J. Biol. Chem. 286, 41246-52, (2011). View articlePMID: 21994945

Further reading

2. Novel conserved domains in proteins with predicted roles in eukaryotic cell-cycle regulation, decapping and RNA stability. Anantharaman V, Aravind L. BMC Genomics 5, 45, (2004). View articlePMID: 15257761

Cross References

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