D
IPR004843

Calcineurin-like phosphoesterase domain, ApaH type

InterPro entry
Short nameCalcineurin-like_PHP_ApaH
Overlapping
homologous
superfamilies
 
domain relationships

Description

This domain is found in a diverse range of phosphoesterases
[1]
, including bis(5'-nucleosyl)-tetraphosphatase (apaH), nucleotidases, sphingomyelin phosphodiesterases and 2'-3' cAMP phosphodiesterases, as well as nucleases such as bacterial SbcD or archaeal/yeast Mre11. The most conserved regions in this domain centre around the metal chelating residues.

References

1.Phosphoesterase domains associated with DNA polymerases of diverse origins. Aravind L, Koonin EV. Nucleic Acids Res. 26, 3746-52, (1998). View articlePMID: 9685491

GO terms

biological process

  • None

cellular component

  • None

Cross References

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