F
IPR005216

Citrate lyase ligase

InterPro entry
Short nameCitrate_lyase_ligase
Overlapping
homologous
superfamilies
 

Description

[Citrate (pro-3S)-lyase] ligase (
6.2.1.22
), also known as citrate lyase ligase, is responsible for acetylation of the prosthetic group (2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase. It converts the inactive thiol form of the enzyme to the active form. In Clostridium sphenoides, citrate lyase ligase actively degrades citrate. In Clostridium sporosphaeroides and Lactococcus lactis, however, the enzyme is under stringent regulatory control. The enzyme's activity in anaerobic bacteria is modulated by phosphorylation and dephosphorylation
[1]
.

References

1.Covalent modification of citrate lyase ligase from Clostridium sphenoides by phosphorylation/dephosphorylation. Antranikian G, Herzberg C, Gottschalk G. Eur. J. Biochem. 153, 413-20, (1985). View articlePMID: 3935436

GO terms

biological process

  • None

cellular component

  • None

Cross References

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