F
IPR005515

Vitelline membrane outer layer protein I (VOMI)

InterPro entry
Short nameVOMI
Overlapping
homologous
superfamilies
 

Description

Vitelline membrane outer layer protein I (VMO-I) is one of the proteins found in the outer layer of the vitelline membrane of eggs. VMO-I, lysozyme, and VMO-II are bound tightly to ovomucin fibrils of the egg yolk membrane. The structure of VMO-I
[1]
consists of three β-sheets forming Greek key motifs, which are related by an internal pseudo three-fold symmetry. It is a member of the β-prism-fold family and the structure of VOM-I has strong similarity to the structure of the delta-endotoxin, as well as a carbohydrate-binding site in the top region of the common fold
[2]
. VMO-I has been shown to synthesize N-acetylchito-oligosaccharides from N-acetylglucosamine.

References

1.Crystal structure of vitelline membrane outer layer protein I (VMO-I): a folding motif with homologous Greek key structures related by an internal three-fold symmetry. Shimizu T, Vassylyev DG, Kido S, Doi Y, Morikawa K. EMBO J. 13, 1003-10, (1994). View articlePMID: 8131734

2.The beta-prism: a new folding motif. Shimizu T, Morikawa K. Trends Biochem. Sci. 21, 3-6, (1996). View articlePMID: 8848836

Contributing Member Database Entries
This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our Privacy Notice and Terms of Use.