R
IPR006691

DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat

InterPro entry
Short nameGyrA/parC_rep
Overlapping
homologous
superfamilies
 

Description

This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 β strands and to probably form a β-propeller structure
[1]
. This region has been shown to bind DNA non-specifically and may stabilise the DNA-topoisomerase complex
[2]
.

References

1.C-terminal domain of gyrase A is predicted to have a beta-propeller structure. Qi Y, Pei J, Grishin NV. Proteins 47, 258-64, (2002). View articlePMID: 11948780

2.DNA gyrase: structure and function. Reece RJ, Maxwell A. Crit. Rev. Biochem. Mol. Biol. 26, 335-75, (1991). View articlePMID: 1657531

GO terms

Cross References

Contributing Member Database Entry
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