IPR007440
Chorismate--pyruvate lyase
InterPro entry
Short name | Chorismate--pyruvate_lyase |
Overlapping homologous superfamilies |
Description
Chorismate--pyruvate lyase catalyses the first step in ubiquinone synthesis, the removal of pyruvate from chorismate, to yield 4-hydroxybenzoate in Escherichia coli and other Gram-negative bacteria
[1]. The yeast Saccharomyces cerevisiae can synthesize ubiquinone from either chorismate or tyrosine
[2], however this enzyme is found only in bacteria. Its activity does not require metal cofactors
[3].
References
1.Cloning and sequencing of Escherichia coli ubiC and purification of chorismate lyase. Nichols BP, Green JM. J. Bacteriol. 174, 5309-16, (1992). View articlePMID: 1644758
2.Ubiquinone biosynthesis in microorganisms. Meganathan R. FEMS Microbiol. Lett. 203, 131-9, (2001). View articlePMID: 11583838
GO terms
biological process
molecular function
cellular component
Cross References
ENZYME
Genome Properties
Representative structure
1tt8: CHORISMATE LYASE WITH PRODUCT, 1.0 A RESOLUTION