D
IPR007635

Tis11B-like protein, N-terminal

InterPro entry
Short nameTis11B_N

Description

All proteins of containing this domain also contain a tandem repeat of CCCH zinc fingers (
IPR000571
). Tis11B, Tis11D and their homologues are thought to be regulatory proteins involved in the response to growth factors
[1]
. Tis11B (
Q07352
) is thought to be involved in calcium signalling-induced apoptosis in B cells
[2]
. The function of this N-terminal domain is unknown.

References

1.The nucleotide sequence of a cDNA encoding an EGF-inducible gene indicates the existence of a new family of mitogen-induced genes. Gomperts M, Pascall JC, Brown KD. Oncogene 5, 1081-3, (1990). PMID: 1695727

2.Distinct mechanisms for rescue from apoptosis in Ramos human B cells by signaling through CD40 and interleukin-4 receptor: role for inhibition of an early response gene, Berg36. Ning ZQ, Norton JD, Li J, Murphy JJ. Eur. J. Immunol. 26, 2356-63, (1996). View articlePMID: 8898945

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