R
IPR009223

Adenomatous polyposis coli protein repeat

InterPro entry
Short nameAPC_rpt

Description

This short region is found repeated in the mid region of the adenomatous polyposis proteins (APCs). In the human protein many cancer-linked SNPs are found near the first three occurrences of the motif. These repeats bind beta-catenin
[1]
.

References

1.Identification of a brain-specific APC homologue, APCL, and its interaction with beta-catenin. Nakagawa H, Murata Y, Koyama K, Fujiyama A, Miyoshi Y, Monden M, Akiyama T, Nakamura Y. Cancer Res. 58, 5176-81, (1998). View articlePMID: 9823329

GO terms

molecular function

  • None

cellular component

  • None
Contributing Member Database Entry
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