Tyrosyl-DNA phosphodiesterase I
Short name | Tdp1 |
Description
References
1.Conversion of phosphoglycolate to phosphate termini on 3' overhangs of DNA double strand breaks by the human tyrosyl-DNA phosphodiesterase hTdp1. Inamdar KV, Pouliot JJ, Zhou T, Lees-Miller SP, Rasouli-Nia A, Povirk LF. J. Biol. Chem. 277, 27162-8, (2002). View articlePMID: 12023295
2.Tyrosyl-DNA phosphodiesterase and the repair of 3'-phosphoglycolate-terminated DNA double-strand breaks. Zhou T, Akopiants K, Mohapatra S, Lin PS, Valerie K, Ramsden DA, Lees-Miller SP, Povirk LF. DNA Repair (Amst.) 8, 901-11, (2009). View articlePMID: 19505854
Further reading
3. Human Tdp1 cleaves a broad spectrum of substrates, including phosphoamide linkages. Interthal H, Chen HJ, Champoux JJ. J. Biol. Chem. 280, 36518-28, (2005). View articlePMID: 16141202
GO terms
biological process
molecular function
cellular component
Cross References
ENZYME