D
IPR010483

Alpha-2-macroglobulin RAP, C-terminal

InterPro entry
Short nameAlpha_2_MRAP_C
Overlapping
homologous
superfamilies
 

Description

The alpha-2-macroglobulin receptor-associated protein (RAP) is a intracellular glycoprotein that binds to the 2-macroglobulin receptor and other members of the low density lipoprotein receptor family. The protein inhibits binding of all currently known ligands of these receptors
[1]
. Two different studies have provided conflicting domain boundaries.

References

1.The solution structure of the N-terminal domain of alpha2-macroglobulin receptor-associated protein. Nielsen PR, Ellgaard L, Etzerodt M, Thogersen HC, Poulsen FM. Proc. Natl. Acad. Sci. U.S.A. 94, 7521-5, (1997). View articlePMID: 9207124

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