IPR010483
Alpha-2-macroglobulin RAP, C-terminal
InterPro entry
Short name | Alpha_2_MRAP_C |
Overlapping homologous superfamilies |
Description
The alpha-2-macroglobulin receptor-associated protein (RAP) is a intracellular glycoprotein that binds to the 2-macroglobulin receptor and other members of the low density lipoprotein receptor family. The protein inhibits binding of all currently known ligands of these receptors
[1]. Two different studies have provided conflicting domain boundaries.
References
1.The solution structure of the N-terminal domain of alpha2-macroglobulin receptor-associated protein. Nielsen PR, Ellgaard L, Etzerodt M, Thogersen HC, Poulsen FM. Proc. Natl. Acad. Sci. U.S.A. 94, 7521-5, (1997). View articlePMID: 9207124
GO terms
biological process
- None
molecular function
cellular component
Contributing Member Database Entry
- Pfam:PF06401