H
IPR011322

Nitrogen regulatory PII-like, alpha/beta

InterPro entry
Short nameN-reg_PII-like_a/b
Overlapping entries
 
UPF0166 (IPR003793)

Description

This superfamily represents a structural domain found in the nitrogen regulatory protein PII, in ATP phosphribosyltransferases (C-terminal domain), in the divalent ion tolerance protein CutA1, and in some bacterial hypothetical proteins. This domain consists of a ferredoxin-like α/β sandwich, which forms trimeric structures with orthogonally packed β-sheets around a three-fold axis.

References

1. Characterization of three different nitrogen-regulated promoter regions for the expression of glnB and glnA in Azospirillum brasilense. de Zamaroczy M, Delorme F, Elmerich C. Mol. Gen. Genet. 224, 421-30, (1990). View articlePMID: 1702507

2. Characterization of pII family (GlnK1, GlnK2, and GlnB) protein uridylylation in response to nitrogen availability for Rhodopseudomonas palustris. Connelly HM, Pelletier DA, Lu TY, Lankford PK, Hettich RL. Anal. Biochem. 357, 93-104, (2006). View articlePMID: 16860774

3. The structure of Escherichia coli ATP-phosphoribosyltransferase: identification of substrate binding sites and mode of AMP inhibition. Lohkamp B, McDermott G, Campbell SA, Coggins JR, Lapthorn AJ. J. Mol. Biol. 336, 131-44, (2004). View articlePMID: 14741209

4. The evolutionarily conserved trimeric structure of CutA1 proteins suggests a role in signal transduction. Arnesano F, Banci L, Benvenuti M, Bertini I, Calderone V, Mangani S, Viezzoli MS. J. Biol. Chem. 278, 45999-6006, (2003). View articlePMID: 12949080

5. Molecular genetics of a chromosomal locus involved in copper tolerance in Escherichia coli K-12. Fong ST, Camakaris J, Lee BT. Mol. Microbiol. 15, 1127-37, (1995). View articlePMID: 7623666

6. Cloning, crystallization and preliminary X-ray studies of XC2981 from Xanthomonas campestris, a putative CutA1 protein involved in copper-ion homeostasis. Lin CH, Chin KH, Gao FP, Lyu PC, Shr HL, Wang AH, Chou SH. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 62, 1113-5, (2006). PMID: 17077491

Cross References

This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our Privacy Notice and Terms of Use.