IPR011611
Carbohydrate kinase PfkB
InterPro entry
Short name | PfkB_dom |
Overlapping homologous superfamilies | |
domain relationships |
Description
This domain is found in a variety of carbohydrate and pyrimidine kinases. It is found in phosphomethylpyrimidine kinase (
2.7.4.7), which is part of the thiamine pyrophosphate (TPP) synthesis pathway -TPP being an essential cofactor for many enzymes
[1]. It is also found in 2-keto-3-deoxygluconate kinase, which is a component of the Entner-Doudoroff pathway in hyperthermophilic archaea
[2].
References
1.Structure of Escherichia coli ribokinase in complex with ribose and dinucleotide determined to 1.8 A resolution: insights into a new family of kinase structures. Sigrell JA, Cameron AD, Jones TA, Mowbray SL. Structure 6, 183-93, (1998). View articlePMID: 9519409
Cross References
ENZYME
Genome Properties
Contributing Member Database Entry
- Pfam:PF00294
Representative structure
4wjm: Crystal structure of Fructokinase from Brucella abortus 2308 with bound AMPPNP