IPR011913
RfaE bifunctional protein, domain I
InterPro entry
Short name | RfaE_dom_I |
Overlapping homologous superfamilies | |
domain relationships |
Description
RfaE is a protein involved in the biosynthesis of ADP-L-glycero-D-manno-heptose, a precursor for LPS inner core biosynthesis. RfaE is a bifunctional protein in Escherichia coli, and separate proteins in some other genome. The longer, N-terminal domain I (this family) is suggested to act in D-glycero-D-manno-heptose 1-phosphate biosynthesis, while domain II (
IPR011914) adds ADP to yield ADP-D-glycero-D-manno-heptose
[1].
References
1.The rfaE gene from Escherichia coli encodes a bifunctional protein involved in biosynthesis of the lipopolysaccharide core precursor ADP-L-glycero-D-manno-heptose. Valvano MA, Marolda CL, Bittner M, Glaskin-Clay M, Simon TL, Klena JD. J. Bacteriol. 182, 488-97, (2000). View articlePMID: 10629197
GO terms
biological process
molecular function
cellular component
- None
Cross References
ENZYME
Genome Properties