D
IPR011913

RfaE bifunctional protein, domain I

InterPro entry
Short nameRfaE_dom_I
Overlapping
homologous
superfamilies
 
Ribokinase-like (IPR029056)
domain relationships

Description

RfaE is a protein involved in the biosynthesis of ADP-L-glycero-D-manno-heptose, a precursor for LPS inner core biosynthesis. RfaE is a bifunctional protein in Escherichia coli, and separate proteins in some other genome. The longer, N-terminal domain I (this family) is suggested to act in D-glycero-D-manno-heptose 1-phosphate biosynthesis, while domain II (
IPR011914
) adds ADP to yield ADP-D-glycero-D-manno-heptose
[1]
.

References

1.The rfaE gene from Escherichia coli encodes a bifunctional protein involved in biosynthesis of the lipopolysaccharide core precursor ADP-L-glycero-D-manno-heptose. Valvano MA, Marolda CL, Bittner M, Glaskin-Clay M, Simon TL, Klena JD. J. Bacteriol. 182, 488-97, (2000). View articlePMID: 10629197

GO terms

Cross References

Contributing Member Database Entries
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