D
IPR012425

DmpG-like communication

InterPro entry
Short nameDmpG_comm

Description

This domain is found towards the C-terminal region of various aldolase enzymes. It consists of five α-helices, four of which form an antiparallel helical bundle that plugs the C terminus of the N-terminal TIM barrel domain
[1]
. The communication domain is thought to play an important role in the heterodimerisation of the enzyme
[1]
.

References

1.Crystal structure of a bifunctional aldolase-dehydrogenase: sequestering a reactive and volatile intermediate. Manjasetty BA, Powlowski J, Vrielink A. Proc. Natl. Acad. Sci. U.S.A. 100, 6992-7, (2003). View articlePMID: 12764229

GO terms

cellular component

  • None

Cross References

Contributing Member Database Entry
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