Protein kinase, ATP binding site
Short name | Protein_kinase_ATP_BS |
Description
* Serine/threonine-protein kinases
* Tyrosine-protein kinases
* Dual specificity protein kinases (e.g. MEK -phosphorylates both Thr and Tyr on target proteins)
References
1.The protein kinase complement of the human genome. Manning G, Whyte DB, Martinez R, Hunter T, Sudarsanam S. Science 298, 1912-34, (2002). View articlePMID: 12471243
2.Genomic analysis of the eukaryotic protein kinase superfamily: a perspective. Hanks SK. Genome Biol. 4, 111, (2003). View articlePMID: 12734000
3.Protein kinases 6. The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification. Hanks SK, Hunter T. FASEB J. 9, 576-96, (1995). View articlePMID: 7768349
4.Protein kinase classification. Hunter T. Meth. Enzymol. 200, 3-37, (1991). View articlePMID: 1835513
5.Protein kinase catalytic domain sequence database: identification of conserved features of primary structure and classification of family members. Hanks SK, Quinn AM. Meth. Enzymol. 200, 38-62, (1991). View articlePMID: 1956325
6.The protein kinase family: conserved features and deduced phylogeny of the catalytic domains. Hanks SK, Quinn AM, Hunter T. Science 241, 42-52, (1988). View articlePMID: 3291115
7.Evolution of protein kinase signaling from yeast to man. Manning G, Plowman GD, Hunter T, Sudarsanam S. Trends Biochem. Sci. 27, 514-20, (2002). View articlePMID: 12368087
8.High-throughput structural biology in drug discovery: protein kinases. Stout TJ, Foster PG, Matthews DJ. Curr. Pharm. Des. 10, 1069-82, (2004). View articlePMID: 15078142
9.Creating chemical diversity to target protein kinases. Li B, Liu Y, Uno T, Gray N. Comb. Chem. High Throughput Screen. 7, 453-72, (2004). View articlePMID: 15320712
GO terms
Cross References
Contributing Member Database Entry
- PROSITE patterns:PS00107