F
IPR017648

5-keto-4-deoxy-D-glucarate aldolase

InterPro entry
Short nameGarL
Overlapping
homologous
superfamilies
 

Description

5-keto-4-deoxy-D-glucarate aldolase GarL is involved in step 2 of the subpathway that synthesizes D-glycerate from galactarate. It catalyses the reversible retro-aldol cleavage of both 5-keto-4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde
[1]
.

References

1.Evolution of enzymatic activities in the enolase superfamily: characterization of the (D)-glucarate/galactarate catabolic pathway in Escherichia coli. Hubbard BK, Koch M, Palmer DR, Babbitt PC, Gerlt JA. Biochemistry 37, 14369-75, (1998). View articlePMID: 9772162

GO terms

Cross References

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