IPR017648
5-keto-4-deoxy-D-glucarate aldolase
InterPro entry
Short name | GarL |
Overlapping homologous superfamilies |
Description
5-keto-4-deoxy-D-glucarate aldolase GarL is involved in step 2 of the subpathway that synthesizes D-glycerate from galactarate. It catalyses the reversible retro-aldol cleavage of both 5-keto-4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde
[1].
References
1.Evolution of enzymatic activities in the enolase superfamily: characterization of the (D)-glucarate/galactarate catabolic pathway in Escherichia coli. Hubbard BK, Koch M, Palmer DR, Babbitt PC, Gerlt JA. Biochemistry 37, 14369-75, (1998). View articlePMID: 9772162
GO terms
biological process
molecular function
cellular component
- None
Cross References
ENZYME
Genome Properties
Representative structure
1dxe: 2-dehydro-3-deoxy-galactarate aldolase from Escherichia coli