S
IPR018520

Di-trans-poly-cis-decaprenylcistransferase-like, conserved site

InterPro entry
Short nameUPP_synth-like_CS

Description

Synonym(s): Di-trans-poly-cis-undecaprenyl-diphosphate synthase, Undecaprenyl pyrophosphate synthetase, Undecaprenyl pyrophosphate synthase, UPP synthetase

Di-trans-poly-cis-decaprenylcistransferase (
2.5.1.31
) (UPP synthetase) generates undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP)
[1]
. This bacterial enzyme is also found in archaebacteria and in a number of uncharacterised proteins including some from yeasts.

This conserved pattern is found towards the C-terminal region in many of the proteins in this entry. The proteins are of about 26 to 40kDa whose central region is well conserved. This pattern also hits related enzymes such as dehydrodolichyl diphosphate synthase.

References

1.Use of genomics to identify bacterial undecaprenyl pyrophosphate synthetase: cloning, expression, and characterization of the essential uppS gene. Apfel CM, Takacs B, Fountoulakis M, Stieger M, Keck W. J. Bacteriol. 181, 483-92, (1999). View articlePMID: 9882662

GO terms

biological process

  • None

cellular component

  • None

Cross References

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