IPR019025
Cordon-bleu, ubiquitin-like domain
InterPro entry
Short name | Cordon-bleu_ubiquitin_domain |
Description
The Cordon-bleu protein domain is highly conserved among vertebrates. The sequence contains three repeated lysine, arginine, and proline-rich regions, the KKRAP motif. The exact function of the protein is unknown but it is thought to be involved in mid-brain neural tube closure. It is expressed specifically in the node
[1]. This domain has a ubiquitin-like fold.
References
1.Cordon-bleu is a conserved gene involved in neural tube formation. Carroll EA, Gerrelli D, Gasca S, Berg E, Beier DR, Copp AJ, Klingensmith J. Dev. Biol. 262, 16-31, (2003). View articlePMID: 14512015
Contributing Member Database Entry
- Pfam:PF09469