D
IPR019025

Cordon-bleu, ubiquitin-like domain

InterPro entry
Short nameCordon-bleu_ubiquitin_domain

Description

The Cordon-bleu protein domain is highly conserved among vertebrates. The sequence contains three repeated lysine, arginine, and proline-rich regions, the KKRAP motif. The exact function of the protein is unknown but it is thought to be involved in mid-brain neural tube closure. It is expressed specifically in the node
[1]
. This domain has a ubiquitin-like fold.

References

1.Cordon-bleu is a conserved gene involved in neural tube formation. Carroll EA, Gerrelli D, Gasca S, Berg E, Beier DR, Copp AJ, Klingensmith J. Dev. Biol. 262, 16-31, (2003). View articlePMID: 14512015

Contributing Member Database Entry
This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our Privacy Notice and Terms of Use.