F
IPR019917

FMN reductase (NADH) RutF

InterPro entry
Short nameRutF
Overlapping
homologous
superfamilies
 

Description

The Rut pathway allows cells to use pyrimidines as sole nitrogen source. The function of RutF in this pathway is to reduce FMN, producing FMNH2 which is subsequently used by RutA in opening the pyrimidine ring
[1, 3, 2]
.

References

1.A previously undescribed pathway for pyrimidine catabolism. Loh KD, Gyaneshwar P, Markenscoff Papadimitriou E, Fong R, Kim KS, Parales R, Zhou Z, Inwood W, Kustu S. Proc. Natl. Acad. Sci. U.S.A. 103, 5114-9, (2006). View articlePMID: 16540542

2.The Rut pathway for pyrimidine degradation: novel chemistry and toxicity problems. Kim KS, Pelton JG, Inwood WB, Andersen U, Kustu S, Wemmer DE. J. Bacteriol. 192, 4089-102, (2010). View articlePMID: 20400551

3.Catalysis of a flavoenzyme-mediated amide hydrolysis. Mukherjee T, Zhang Y, Abdelwahed S, Ealick SE, Begley TP. J. Am. Chem. Soc. 132, 5550-1, (2010). View articlePMID: 20369853

GO terms

biological process

  • None

cellular component

  • None

Cross References

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