D
IPR020573

UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region

InterPro entry
Short nameUDP_GlcNAc_AcTrfase_non-rep
Overlapping
homologous
superfamilies
 

Description

This entry represents the non-repeating region of the enzyme.

UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase (
2.3.1
) catalyses an early step in lipid A biosynthesis
[1]
:UDP-3-O-(3-hydroxytetradecanoyl)glucosamine + (R)-3-hydroxytetradecanoyl- [acyl carrier protein] = UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + [acyl carrier protein] This enzyme contains several hexapeptide repeats and forms part of the wider bacterial transferase hexapeptide repeat family.

References

1.The firA gene of Escherichia coli encodes UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase. The third step of endotoxin biosynthesis. Kelly TM, Stachula SA, Raetz CR, Anderson MS. J. Biol. Chem. 268, 19866-74, (1993). View articlePMID: 8366125

GO terms

Cross References

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