IPR020573
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region
InterPro entry
Short name | UDP_GlcNAc_AcTrfase_non-rep |
Overlapping homologous superfamilies |
Description
This entry represents the non-repeating region of the enzyme.
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase (
2.3.1) catalyses an early step in lipid A biosynthesis
[1]:UDP-3-O-(3-hydroxytetradecanoyl)glucosamine + (R)-3-hydroxytetradecanoyl- [acyl carrier protein] = UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + [acyl carrier protein]
This enzyme contains several hexapeptide repeats and forms part of the wider bacterial transferase hexapeptide repeat family.
References
1.The firA gene of Escherichia coli encodes UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase. The third step of endotoxin biosynthesis. Kelly TM, Stachula SA, Raetz CR, Anderson MS. J. Biol. Chem. 268, 19866-74, (1993). View articlePMID: 8366125
GO terms
biological process
molecular function
cellular component
- None
Cross References
ENZYME
Contributing Member Database Entry
- Pfam:PF04613