D
IPR022531

RNA-directed RNA polymerase L, PA-C-like domain

InterPro entry
Short nameL_PA-C-like

Description

This domain is found in RNA-directed RNA polymerase L from Bunyavirales. This has been described as the PA-C like domain, which forms a narrow and positively charged cleft with the thumb domain, where the 3' RNA is likely bound
[1]
.

References

1.Structural and functional characterization of the severe fever with thrombocytopenia syndrome virus L protein. Vogel D, Thorkelsson SR, Quemin ERJ, Meier K, Kouba T, Gogrefe N, Busch C, Reindl S, Gunther S, Cusack S, Grunewald K, Rosenthal M. Nucleic Acids Res 48, 5749-5765, (2020). PMID: 32313945

Cross References

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