H
IPR023382

tRNA-specific 2-thiouridylase MnmA-like, central domain superfamily

InterPro entry
Short nameMnmA-like_central_sf
Overlapping entries
 

Description

This entry represents the central PRC-barrel domain of tRNA-specific 2-thiouridylase MnmA and similar proteins from bacteria and eukaryotes. MnmA catalyses the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s2U34
[2, 1]
.

References

1.Transfer RNA(5-methylaminomethyl-2-thiouridine)-methyltransferase from Escherichia coli K-12 has two enzymatic activities. Hagervall TG, Edmonds CG, McCloskey JA, Bjork GR. J. Biol. Chem. 262, 8488-95, (1987). View articlePMID: 3298234

2.Snapshots of tRNA sulphuration via an adenylated intermediate. Numata T, Ikeuchi Y, Fukai S, Suzuki T, Nureki O. Nature 442, 419-24, (2006). View articlePMID: 16871210

GO terms

biological process

  • None

cellular component

  • None

Cross References

Contributing Member Database Entry
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