IPR023464
DNA-directed RNA polymerase subunit Rpo12
InterPro entry
Short name | Rpo12 |
Overlapping homologous superfamilies | |
family relationships |
Description
DNA-directed RNA polymerases, also known as DNA-dependent RNA polymerases, are responsible for the polymerisation of ribonucleotides into a sequence complementary to the template DNA. Eukaryotes have three different DNA-directed RNA polymerases (RNAPs), Pol I, II, and III, whereas Archaea and Bacteria have single enzymes.
References
1.Archaeal RNA polymerase. Hirata A, Murakami KS. Curr. Opin. Struct. Biol. 19, 724-31, (2009). View articlePMID: 19880312
2.Evolution of Complex RNA Polymerases: The Complete Archaeal RNA Polymerase Structure. Korkhin Y, Unligil UM, Littlefield O, Nelson PJ, Stuart DI, Sigler PB, Bell SD, Abrescia NG. PLoS Biol. 7, e102, (2009). View articlePMID: 19419240
3.Archaeal RNA polymerase subunits F and P are bona fide homologs of eukaryotic RPB4 and RPB12. Werner F, Eloranta JJ, Weinzierl RO. Nucleic Acids Res. 28, 4299-305, (2000). View articlePMID: 11058130
GO terms
biological process
cellular component
- None
Cross References
ENZYME
Contributing Member Database Entry
- HAMAP:MF_00615