F
IPR023943

Enolase-phosphatase E1

InterPro entry
Short nameEnolase-ppase_E1
Overlapping
homologous
superfamilies
 
HAD superfamily (IPR023214)
family relationships

Description

This enzyme is the enolase-phosphatase of methionine salvage, a pathway that regenerates methionine from methylthioadenosine (MTA). Adenosylmethionine (AdoMet) is a donor of different moieties for various processes, including methylation reactions. Use of AdoMet for spermidine biosynthesis, which leads to polyamine biosynthesis, leaves MTA as a by-product that must be cleared. In Bacillus subtilis and related species, this single protein is replaced by separate enzymes with enolase and phosphatase activities.

This entry also matches a number of probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 enzymes.

GO terms

Cross References

Contributing Member Database Entries
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