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IPR027442

MAP kinase activated protein kinase, C-terminal

InterPro entry
Short nameMAPKAPK_C

Description

This superfamily represent the C-terminal domain of the MAP kinase activated protein kinases (MAPKAPKs). Proteins containing this domain include Mapkapk2 and Mapkapk3. They are mainly involved in post-transcriptional regulation of gene expression and play an role in inflammation and cancer
[1]
.

References

1.MAPKAP kinases MK2 and MK3 in inflammation: complex regulation of TNF biosynthesis via expression and phosphorylation of tristetraprolin. Ronkina N, Menon MB, Schwermann J, Tiedje C, Hitti E, Kotlyarov A, Gaestel M. Biochem. Pharmacol. 80, 1915-20, (2010). View articlePMID: 20599781

Cross References

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