IPR027969
Small membrane A-kinase anchor protein
InterPro entry
Short name | Small_membr_AKAP |
Description
Small membrane A-kinase anchor protein (sm) AKAP binds to type I regulatory subunits of protein kinase A (PKA-RI) and anchors them to the plasma membrane. This way provides spatio-temporal specificity for cAMP-dependent protein kinase (PKA) signalling
[1]. Small membrane AKAP is localised at the plasma membrane via potential myristoylation/palmitoylation anchors.
References
1.A small novel A-kinase anchoring protein (AKAP) that localizes specifically protein kinase A-regulatory subunit I (PKA-RI) to the plasma membrane. Burgers PP, Ma Y, Margarucci L, Mackey M, van der Heyden MA, Ellisman M, Scholten A, Taylor SS, Heck AJ. J. Biol. Chem. 287, 43789-97, (2012). View articlePMID: 23115245
GO terms
biological process
- None
molecular function
cellular component
- None