Glycerophosphodiester phosphodiesterase domain
Short name | GP_PDE_dom |
Overlapping homologous superfamilies |
Description
* Bacterial glycerophosphoryl diester phosphodiesterase GlpQ (EC 3.1.4.46).
* Bacterial gylcerophosphoryl diester phosphodiesterase UgpQ (EC 3.1.4.46).
* Mammalian glycerophosphodiester phosphodiesterase 1 (GDE1) (EC 3.1.4.44) (or MMIR16)
* Mammalian glycerophosphodiester phosphodiesterase domain-containing protein 5 (GDPD5) (EC 3.1.-.-) (or GDE2)
* Mammalian glycerophosphoinositol inositolphosphodiesterase GDPD2 (or GDE3) (EC 3.1.4.43)
* Mammalian glycerophosphodiester phosphodiesterase domain-containing protein 1 (GDPD1) (EC 3.1.-.-) (or GDE4)
* Mammalian glycerophosphocholine phosphodiesterase GPCPD1 (EC 3.1.4.2) (or GDE5), selectively hydrolyzes glycerophosphocholine (GroPCho) and controls skeletal muscle development
* Mammalian glycerophosphodiester phosphodiesterase domain-containing protein 4 (GDPD4) (EC 3.1.-.-) (or GDE6)
References
1.Crystal structure of a glycerophosphodiester phosphodiesterase (GDPD) from Thermotoga maritima (TM1621) at 1.60 A resolution. Santelli E, Schwarzenbacher R, McMullan D, Biorac T, Brinen LS, Canaves JM, Cambell J, Dai X, Deacon AM, Elsliger MA, Eshagi S, Floyd R, Godzik A, Grittini C, Grzechnik SK, Jaroszewski L, Karlak C, Klock HE, Koesema E, Kovarik JS, Kreusch A, Kuhn P, Lesley SA, McPhillips TM, Miller MD, Morse A, Moy K, Ouyang J, Page R, Quijano K, Rezezadeh F, Robb A, Sims E, Spraggon G, Stevens RC, van den Bedem H, Velasquez J, Vincent J, von Delft F, Wang X, West B, Wolf G, Xu Q, Hodgson KO, Wooley J, Wilson IA. Proteins 56, 167-70, (2004). View articlePMID: 15162496
2.Crystal structure of glycerophosphodiester phosphodiesterase from Agrobacterium tumefaciens by SAD with a large asymmetric unit. Rao KN, Bonanno JB, Burley SK, Swaminathan S. Proteins 65, 514-8, (2006). View articlePMID: 16909422
3.GDE1/MIR16 is a glycerophosphoinositol phosphodiesterase regulated by stimulation of G protein-coupled receptors. Zheng B, Berrie CP, Corda D, Farquhar MG. Proc. Natl. Acad. Sci. U.S.A. 100, 1745-50, (2003). View articlePMID: 12576545
4.Isolation and characterization of two serpentine membrane proteins containing glycerophosphodiester phosphodiesterase, GDE2 and GDE6. Nogusa Y, Fujioka Y, Komatsu R, Kato N, Yanaka N. Gene 337, 173-9, (2004). View articlePMID: 15276213
5.Novel membrane protein containing glycerophosphodiester phosphodiesterase motif is transiently expressed during osteoblast differentiation. Yanaka N, Imai Y, Kawai E, Akatsuka H, Wakimoto K, Nogusa Y, Kato N, Chiba H, Kotani E, Omori K, Sakurai N. J. Biol. Chem. 278, 43595-602, (2003). View articlePMID: 12933806
6.Isolation, characterization and molecular 3D model of human GDE4, a novel membrane protein containing glycerophosphodiester phosphodiesterase domain. Chang PA, Shao HB, Long DX, Sun Q, Wu YJ. Mol. Membr. Biol. 25, 557-66, (2008). View articlePMID: 18991142
7.A novel glycerophosphodiester phosphodiesterase, GDE5, controls skeletal muscle development via a non-enzymatic mechanism. Okazaki Y, Ohshima N, Yoshizawa I, Kamei Y, Mariggio S, Okamoto K, Maeda M, Nogusa Y, Fujioka Y, Izumi T, Ogawa Y, Shiro Y, Wada M, Kato N, Corda D, Yanaka N. J. Biol. Chem. 285, 27652-63, (2010). View articlePMID: 20576599
GO terms
biological process
molecular function
cellular component
- None
Cross References
ENZYME
Genome Properties