Sterol O-acyltransferase, metazoa
Short name | Sterol_acyltranf_meta |
family relationships |
Description
References
1.Differential expression of ACAT1 and ACAT2 among cells within liver, intestine, kidney, and adrenal of nonhuman primates. Lee RG, Willingham MC, Davis MA, Skinner KA, Rudel LL. J. Lipid Res. 41, 1991-2001, (2000). PMID: 11108732
2.ACAT-2, a second mammalian acyl-CoA:cholesterol acyltransferase. Its cloning, expression, and characterization. Cases S, Novak S, Zheng YW, Myers HM, Lear SR, Sande E, Welch CB, Lusis AJ, Spencer TA, Krause BR, Erickson SK, Farese RV Jr. J. Biol. Chem. 273, 26755-64, (1998). View articlePMID: 9756919
3.Deletion of sterol O-acyltransferase 2 (SOAT2) function in mice deficient in lysosomal acid lipase (LAL) dramatically reduces esterified cholesterol sequestration in the small intestine and liver. Lopez AM, Posey KS, Turley SD. Biochem. Biophys. Res. Commun. 454, 162-166, (2014). PMID: 25450374
4.Characterization of two human genes encoding acyl coenzyme A:cholesterol acyltransferase-related enzymes. Oelkers P, Behari A, Cromley D, Billheimer JT, Sturley SL. J. Biol. Chem. 273, 26765-71, (1998). View articlePMID: 9756920
5.Human acyl-CoA:cholesterol acyltransferase (ACAT) and its potential as a target for pharmaceutical intervention against atherosclerosis. Chang C, Dong R, Miyazaki A, Sakashita N, Zhang Y, Liu J, Guo M, Li BL, Chang TY. Acta Biochim. Biophys. Sin. (Shanghai) 38, 151-6, (2006). View articlePMID: 16518538
GO terms
biological process
molecular function
cellular component
Cross References
ENZYME
Contributing Member Database Entry
- PIRSF:PIRSF500230