D
IPR032778

Growth factor receptor domain 4

InterPro entry
Short nameGF_recep_IV
Overlapping
homologous
superfamilies
 

Description

This is the fourth extracellular domain of receptor tyrosine protein kinases. Interaction between this domain and the furin-like domain (
IPR006211
) regulates the binding of ligands to the receptor L domains (
IPR000494
)
[1]
.

References

1.Structure of the extracellular region of HER3 reveals an interdomain tether. Cho HS, Leahy DJ. Science 297, 1330-3, (2002). View articlePMID: 12154198

Cross References

Contributing Member Database Entry
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