F
IPR033682

Palmitoyltransferase PFA4

InterPro entry
Short namePFA4

Description

Palmitoyltransferase PFA4 mediates the reversible addition of palmitate to target proteins, allowing them to associate with membranes
[2]
. Saccharomyces cerevisiae PFA4 has been shown to palmitoylate several amino acid permeases
[1]
, and to palmitoylate chitin synthase CHS3, which is required for its proper export from the ER
[2, 3]
.

References

1.Global analysis of protein palmitoylation in yeast. Roth AF, Wan J, Bailey AO, Sun B, Kuchar JA, Green WN, Phinney BS, Yates JR 3rd, Davis NG. Cell 125, 1003-13, (2006). View articlePMID: 16751107

2.Palmitoylation by the DHHC protein Pfa4 regulates the ER exit of Chs3. Lam KK, Davey M, Sun B, Roth AF, Davis NG, Conibear E. J. Cell Biol. 174, 19-25, (2006). View articlePMID: 16818716

3.In Vitro and In Vivo Studies on the Structural Organization of Chs3 from Saccharomyces cerevisiae. Gohlke S, Muthukrishnan S, Merzendorfer H. Int J Mol Sci 18, (2017). PMID: 28346351

GO terms

Cross References

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