H
IPR042566

L1 transposable element, C-terminal domain

InterPro entry
Short nameL1_C
Overlapping entries
 
Transposase, L1 (IPR004244)

Description

This superfamily represents a conserved component in the protein ORF1 of the long interspersed nuclear element 1 (LINE-1 or L1) retrotransposon. This domain is designated C-terminal and its sole function is to assist RNA binding to the central RRM domain
[1]
.

References

1.Trimeric structure and flexibility of the L1ORF1 protein in human L1 retrotransposition. Khazina E, Truffault V, Buttner R, Schmidt S, Coles M, Weichenrieder O. Nat. Struct. Mol. Biol. 18, 1006-14, (2011). View articlePMID: 21822284

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