H
IPR043036

Phosphoprotein, C-terminal domain, viral

InterPro entry
Short namePhosphoprotein_C_viral
Overlapping entries
 

Description

This superfamily represents the C-terminal domain of the phosphoprotein from vesiculoviruses, which are ssRNA negative-strand rhabdoviruses. It is known as the phosphoprotein or P protein
[1, 2]
. This protein may be part of the RNA dependent RNA polymerase complex
[1]
. The phosphorylation states of this protein may regulate the transcription and replication complexes
[2]
.

Structurally, the C-terminal domain consists of 2 strands and 5 helices.

References

1.Basic amino acid residues at the carboxy-terminal eleven amino acid region of the phosphoprotein (P) are required for transcription but not for replication of vesicular stomatitis virus genome RNA. Das T, Pattnaik AK, Takacs AM, Li T, Hwang LN, Banerjee AK. Virology 238, 103-14, (1997). View articlePMID: 9375014

2.Phosphorylation within the amino-terminal acidic domain I of the phosphoprotein of vesicular stomatitis virus is required for transcription but not for replication. Pattnaik AK, Hwang L, Li T, Englund N, Mathur M, Das T, Banerjee AK. J. Virol. 71, 8167-75, (1997). View articlePMID: 9343167

Contributing Member Database Entry
This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our Privacy Notice and Terms of Use.