E3 ubiquitin-protein ligase ZNF598/Hel2
Short name | ZNF598/Hel2 |
Description
References
1.Collided ribosomes form a unique structural interface to induce Hel2-driven quality control pathways. Ikeuchi K, Tesina P, Matsuo Y, Sugiyama T, Cheng J, Saeki Y, Tanaka K, Becker T, Beckmann R, Inada T. EMBO J 38, (2019). PMID: 30609991
2.ZNF598 and RACK1 Regulate Mammalian Ribosome-Associated Quality Control Function by Mediating Regulatory 40S Ribosomal Ubiquitylation. Sundaramoorthy E, Leonard M, Mak R, Liao J, Fulzele A, Bennett EJ. Mol. Cell 65, 751-760.e4, (2017). View articlePMID: 28132843
3.Initiation of Quality Control during Poly(A) Translation Requires Site-Specific Ribosome Ubiquitination. Juszkiewicz S, Hegde RS. Mol. Cell 65, 743-750.e4, (2017). View articlePMID: 28065601
4.A novel 4EHP-GIGYF2 translational repressor complex is essential for mammalian development. Morita M, Ler LW, Fabian MR, Siddiqui N, Mullin M, Henderson VC, Alain T, Fonseca BD, Karashchuk G, Bennett CF, Kabuta T, Higashi S, Larsson O, Topisirovic I, Smith RJ, Gingras AC, Sonenberg N. Mol. Cell. Biol. 32, 3585-93, (2012). View articlePMID: 22751931
5.Novel E3 ubiquitin ligases that regulate histone protein levels in the budding yeast Saccharomyces cerevisiae. Singh RK, Gonzalez M, Kabbaj MH, Gunjan A. PLoS ONE 7, e36295, (2012). View articlePMID: 22570702
GO terms
biological process
molecular function
cellular component
- None
Cross References
ENZYME
Contributing Member Database Entry
- PANTHER:PTHR22938