F
IPR045122

Calcium permeable stress-gated cation channel 1-like

InterPro entry
Short nameCsc1-like

Description

Csc1 is a cation channel that is permeable to calcium and gated by physical signals such as hyperosmotic stress
[1, 2, 3]
.

References

1.DUF221 proteins are a family of osmosensitive calcium-permeable cation channels conserved across eukaryotes. Hou C, Tian W, Kleist T, He K, Garcia V, Bai F, Hao Y, Luan S, Li L. Cell Res. 24, 632-5, (2014). View articlePMID: 24503647

2.OSCA/TMEM63 are an Evolutionarily Conserved Family of Mechanically Activated Ion Channels. Murthy SE, Dubin AE, Whitwam T, Jojoa-Cruz S, Cahalan SM, Mousavi SAR, Ward AB, Patapoutian A. Elife 7, (2018). PMID: 30382938

3.Heterozygous Variants in the Mechanosensitive Ion Channel TMEM63A Result in Transient Hypomyelination during Infancy. Yan H, Helman G, Murthy SE, Ji H, Crawford J, Kubisiak T, Bent SJ, Xiao J, Taft RJ, Coombs A, Wu Y, Pop A, Li D, de Vries LS, Jiang Y, Salomons GS, van der Knaap MS, Patapoutian A, Simons C, Burmeister M, Wang J, Wolf NI. Am J Hum Genet 105, 996-1004, (2019). PMID: 31587869

GO terms

biological process

  • None

cellular component

  • None
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