F
IPR045258

ArfGAP ACAP1/2/3-like

InterPro entry
Short nameACAP1/2/3-like

Description

ADP-ribosylation factors (ARFs) function in diverse physiological and molecular activities
[2]
. This entry represents a group of GTPase-activating proteins (GAPs) for the ADP ribosylation factors (ARFs). This entry includes ACAP1-3 from animals, Age1 from budding yeasts
[3]
and AGD1-4 from plants. ACAP1 and ACAP2 are Arf6 GTPase-activating proteins that function coordinately in the cell periphery
[4]
. AGD1 is necessary for straight root hair growth in Arabidopsis
[1]
.

References

1.A class I ADP-ribosylation factor GTPase-activating protein is critical for maintaining directional root hair growth in Arabidopsis. Yoo CM, Wen J, Motes CM, Sparks JA, Blancaflor EB. Plant Physiol 147, 1659-74, (2008). PMID: 18539780

2.Structure, organization and evolution of ADP-ribosylation factors in rice and foxtail millet, and their expression in rice. Muthamilarasan M, Mangu VR, Zandkarimi H, Prasad M, Baisakh N. Sci Rep 6, 24008, (2016). PMID: 27097755

3.Four ARF GAPs in Saccharomyces cerevisiae have both overlapping and distinct functions. Zhang CJ, Bowzard JB, Anido A, Kahn RA. Yeast 20, 315-30, (2003). PMID: 12627398

4.ACAPs are arf6 GTPase-activating proteins that function in the cell periphery. Jackson TR, Brown FD, Nie Z, Miura K, Foroni L, Sun J, Hsu VW, Donaldson JG, Randazzo PA. J. Cell Biol. 151, 627-38, (2000). View articlePMID: 11062263

GO terms

biological process

  • None

cellular component

  • None
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